This disrupts the translation initiation complex and provides degradative enzymes with access to the 5′ cap and remaining RNA body. The intimate relationship between mRNA decay and translation ...

and Furuichi et al., revealed that certain viral and eukaryotic mRNAs have a cap — a methylated guanosine residue linked to the 5′ end of mRNA through an inverted 5′ to 5′ triphosphate bridge.

InDevR partners with Aldevron to describe how the VaxArray 5′CapQ assay can be used to measure intact mRNA in a single assay to streamline bioprocess development.

TriLink BioTechnologies & Aldveron ink non-exclusive license and supply agreement for CleanCap mRNA capping technology: San Diego, US Thursday, February 6, 2025, 15:00 Hrs [IST] T ...

kinetoplast mRNA editing) and under conditions of cellular stress (e.g., virus infection, unfolded protein response). RNA cleavage can occur either: (i) by a transesterification mechanism that yields ...

We recently compiled a list of the 12 Best S&P 500 Stocks to Invest in According to Analysts. In this article, we are going ...

The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

(NASDAQ:MRNA) stands against other high growth ... We extracted the stocks that have a healthy 5-year revenue growth and a market cap of more than $10 billion. Finally, the stocks were ranked ...

You can expect three times the transcriptional yield (4 mg/mL) and a much-improved capping efficiency (>95%) over traditional methods. The mRNA cap structure is an important point of consideration for ...