However, the deposition in the myocardium, where amyloid infiltration disrupts calcium transport, receptor modulation, and cellular metabolism, causes restrictive cardiomyopathy and heart failure ...

Amyloidosis is a rare cause of myopathy. Its prominent or presenting feature may be respiratory failure. Physiological measurement of transdiaphragmatic pressure and biopsy specimens of muscle show ...

mayo.edu Amyloid light chain (AL) amyloidosis is a systemic disease characterised by the aggregation of misfolded immunoglobulin light chain (LC), predominantly in the heart and kidneys, causing organ ...

He had carpal tunnel surgery 2 years prior, in which pathology revealed amyloid. Laboratory studies at our institution were as follows: hemoglobin, 13.5 g/dL (normal, 13.5–17.5 g/dL); normal ...

The diagnosis of amyloidosis requires a tissue biopsy that demonstrates apple-green birefringence when stained with Congo Red and viewed with a polarizing microscope. Sulfate Alcian Blue is an ...

His last CT imaging studies of the chest, abdomen and pelvis 8 months after chemotherapy revealed reduction in his overall adenopathy but unchanged amyloid infiltration of the retroperitoneum. His ...

The pathophysiology of conduction disease in CA remains elusive, being most likely the result of the interplay between a variety of mechanisms: autonomic dysfunction, especially in patients with AL or ...

Cardiac MRI was consistent with early amyloid infiltration. We highlight the importance of dermatological manifestations in amyloidosis, to allow for early diagnosis, potentially limiting end organ ...