These superspreaders, amyloid beta 42, form only as secondary structures after an initial amyloid beta fibril has been created (see the diagram below). Nirmalraj and team clarify the shape and ...

Several mutations affecting β-amyloid, either to APP 1,2,3 or to presenilins 4,5, are capable of producing familial forms of AD 6,7,8,9,10,11,12. APP 695 SWE mice expressing transgenic human APP ...

but not with [beta-amyloid]. In experiments using miniature human brain models (organoids), we saw that HSV-1 infection increases the amount of tau,” he told us. Interestingly, Shemesh said ...

In 2020, Cairn and her colleagues showed that if they infected the human brain-like tissue with HSV-1 in the lab, they developed characteristics of Alzheimer’s, including clumps of beta-amyloid.