AD的发生主要是大脑中β-淀粉样蛋白（Aβ）和Tau的异常沉积导致的神经元死亡和一系列病理，而载脂蛋白E（ApoE）是脑部运输Aβ和Tau的最关键蛋白 ...

Further investigations to narrow down the chromosomal region associated with dementia, and to explore the link with APOE, are warranted. The results imply that other tau kinases should be ...

These assays are intended to assess p-Tau217, GFAP, NfL, and APOE ε4 biomarkers ... is a critical biomarker to detect tau and amyloid pathology. Tau and amyloid pathology refer to the abnormal ...