Additionally, single-cell RNA sequencing has revealed time- and sex-specific responses of spinal cord microglia to nerve injury, linking the gene Apolipoprotein E (ApoE) to chronic pain in humans[4].

The APOE gene comes in the variations APOE2 ... levels of a protein known as amyloid in the fluid around the brain and spinal cord which is a sign of Alzheimer’s. Dr Reisa Sperling, professor ...

These genes, that are associated with spinal muscular atrophy (SMA), only differ by a single nucleotide, which requires any copy number solution to have very high assay specificity. For researchers ...