Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia ...

Strategies to detect and modulate the activity of microglia, astrocytes and oligodendrocytes could help tilt the inflammatory balance in the right direction to treat neurodegenerative diseases ...

they transitioned the astrocytes to a pathogenic state by adding microglia-derived cytokines, which are the molecular cues that induce reactivity in neurodegenerative diseases. 2 Using this system to ...

These effects range from the acceleration of neurodegeneration caused by mutant SOD1 acting in astrocytes and microglia to the direct production of degeneration in Purkinje cells by mutant ataxin ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

Alongside microglia, astrocytes play a pivotal role in supporting brain functions, including metabolism, neurotransmitter regulation, and maintaining the BBB. This review critically examines how ...

Xenon is one of the six noble gases. Its name derives from the Greek word for “strange”. In medicine, it has been used as an ...

Alongside microglia, astrocytes play a pivotal role in supporting brain functions, including metabolism, neurotransmitter regulation, and maintaining the BBB. This review critically examines how ...

Differentiation of iPSCs into neurons, astrocytes and microglia allow us to analyze aberrant gene and protein expression, function and metabolism in developing and maturing human brain well before the ...

We use induced pluripotent stem cells (iPSCs) representing neurological and psychiatric diseases. Differentiation of iPSCs into neurons, astrocytes, microglia allow us to analyze aberrant gene and ...