suggesting that extremes of autophagy modulation are maladaptive. Altering the expression of key autophagy genes such as Becn1 (encoding beclin-1, or Atg6) within a physiologically relevant range ...

and evaluate the therapeutic potential of autophagy modulation for cancer treatment. For more information, visit our research lab website.

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...