Amyloid-beta (Aβ): A peptide that aggregates to form amyloid plaques, a hallmark of Alzheimer's disease. Cryo-electron microscopy (cryo-EM): A technique that allows for the visualization of ...
Amyloid diseases result from normal proteins that, for reasons that remain unclear, begin to aggregate into amyloid plaques, which in turn serve as the seed for the formation of new plaques and ...
The beta-amyloid protein forms insoluble aggregates called amyloid plaques in the space between brain cells. In contrast, the tau protein aggregates to form insoluble fibrils, referred to as ...
Amyloid aggregates can form from a number of different ... caused by aggregation of beta-2-microglobulin. [Yancy 2013;15a] Of the cardiomyopathy-causing amyloidoses listed above, the most common ...
Immunohistochemical analyses using specific antibodies were used to confirm the presence of beta ... of soluble aggregates than neurons, with a non-linear relationship between the amyloid β ...