Zoledronate prevents fractures in older women when administered ... the protocol (available with the full text of this article at NEJM.org); and the first author wrote the first draft of the ...

Fractures, by far the most important abnormality ... caused by an imbalance between the formation and the resorption of bone. Throughout life, even after . . . From the Department of Orthopedic ...

Zoledronate prevents fractures when given every 12 to 18 months, but its effects on bone health persist well beyond 5 years. New research findings on very infrequent zoledronate dosing in early ...