UK scientists have identified a new way to kill pancreatic cancer cells by ‘pulling the plug’ on the energy generator that fuels calcium pumps on their cell surface. The study, published in the ...

Cells are preoccupied by the control of cytosolic calcium concentration ... transported across membranes by channels, exchangers and pumps that regulate flux across the ER, mitochondrial and ...

9. The top of site I contains residues that, when mutated, uncouple the pump, permitting calcium-stimulated ATPase activity without transport of the calcium ions 16,18, evidently because the ...

Successful test in breast cancer patients: the active agent digoxin, a cardiac medication, dissolves clusters of circulating breast cancer cells in the blood, thus reducing the risk of metastases ...

Some tumor types spread throughout the body and develop metastases instead of staying at their original location.

Successful test in breast cancer patients: the active agent digoxin, a cardiac medication, dissolves clusters of circulating ...

Certain tumor types do not remain at their point of origin but spread throughout the body and form metastases. This is ...