"For the production of one of the components in the cartilage matrix, known as collagen II, the dancing molecules containing the cyclic peptide that activates the TGF-beta1 receptor were even more ...
Osteoarthritis (OA) is characterized by proteoglycan loss, degradation of type II collagen and subsequent destruction of articular cartilage matrix. Animal experiments have provided strong ...
Articular cartilage erosion is a characteristic feature ... motifs [ADAMTS] enzymes), the collagen network (caused by matrix metalloproteinases [MMPs]) and extracellular matrix proteins.
1 According to popular medical textbooks, cartilage is made up of only one type of specialized cell called a chondrocyte, which is small and secretes large quantities of extracellular matrix, giving ...