ATR and ATM kinases are key factors for the surveillance of DNA replication, and prevent chromosome breakage in dividing cells. However, during repair processes, chromosome fragments can be ...
Aa Aa Aa Eukaryotic genomes are replicated with almost absolute fidelity every time cells divide. However, conditions for DNA replication are rarely ideal. For example, environmental toxins or ...
Original DNA template - DNA is a double helix made of two complementary strands. Each strand can be used as a template to create a new DNA molecule. Free DNA nucleotides – needed to form the new ...
DNA replication is happening continuously throughout ... For example, in cancer -- marked by rapidly dividing cells -- a medicine could potentially kill the cells by accessing them during the ...
In a study that appears in the journal Cell, scientists from San Francisco-based Gladstone Institutes—including co-first author Megan Ostrowski (left) and senior author Vijay Ramani, ...
DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of DNA DNA replication is the process by which a cell makes an identical ...
Most dividing cells in the body have well-defined checkpoint mechanisms to sense and correct DNA damage during DNA replication. Neurons, however, do not divide. For this reason, they are at ...
These drugs interfere with DNA synthesis and replication, leading to the death of rapidly dividing cancer cells. Pyrimidine derivatives, such as leflunomide and teriflunomide, are used as ...