Allogeneic dendritic cells provide both ‘stranger’ and ‘danger’ signals to the immune system that are crucial for it to sense a cell-associated threat such as cancer. These signals ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

gp96 is a powerful immune stimulator that directs antigen cross-presentation and enhances T cell costimulation on activated dendritic cells ... s natural immune system to treat cancer, ...

The immune system has evolved to mount immune responses ... may result in chronic inflammation or autoimmunity. Dendritic cells (DCs) actively participate in maintaining this balance.

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod.

known as conventional type 1 dendritic cells (cDC1s). These cells, located in parts of the gut like the ileum, can activate ...

liver tissue cells and created immune tolerance between two allogeneic mice Liver tissue Interferon-regulatory factor-8 is essential for differentiation and function of dendritic cells and thus for ...

While the immune system works very well most of the time ... One approach had researchers loading dendritic cells with killed AIDS viruses and then injecting them back into the person, triggering ...

the innate immune system, consists of a variety of cell types, including natural killer (NK) cells, macrophages and dendritic cells, that serve as an initial line of defense against threats.

Researchers at MedUni Vienna have developed a combination therapy using systemic interferon-I and topical imiquimod.

The hierarchical structure of the lymphatic system and the dynamic interactions between immune cells and lymphatic endothelium offer an excellent ... via controlled expansion of lymphatic capillary ...