Research in this area has gained momentum, particularly in the context of diabetes treatment, as scientists explore innovative methods to generate, preserve, and transplant islet cells.
Our results show that as a therapy for subjects with unstable, labile diabetes or severe problems with hypoglycemia, islet transplantation can achieve consistent glucose values and alleviate these ...
[25]) Whether the presence of macrophages is causative to type 2 diabetes islet pathology requires further investigation. Hess et al. [26] have shown that bone marrow cells promote islet ...
Three people with type 1 diabetes who received Vertex Pharma’s islet cell therapy VX-880 have been able to come off insulin altogether within a year, raising the prospect of a life without ...
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
(NASDAQ: SANA), a company focused on changing the possible for patients through engineered cells, today announced initial results from an investigator-sponsored, first-in-human study transplanting ...
We view the insights from the current study as directly applicable to developing SC451, our HIP-modified, stem cell-derived pancreatic islet cell program for the treatment of type 1 diabetes.