DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...
Enhancers were formerly believed to be modular. Each enhancer occupies a separate region of DNA, as the term suggests. “We have shown, however, that this is not absolutely true," explained ...
“We didn’t think it would work.” The results serve as an extreme example of what scientists are now recognizing as trends among enhancers—that activity can be conserved over long evolutionary ...
CSHL Professors Thomas Gingeras and Rob Martienssen have launched a new genomic encyclopedia called MaizeCODE. Their latest ...
In a 2010 Nature paper, researchers in the lab of neurobiologist Michael Greenberg at Harvard Medical School reported that enhancers can produce RNA. Working with cultured mouse neurons, the ...
Join Dr. Emily Hodges, assistant professor of biochemistry at Vanderbilt University, to learn more about how the Hodges Lab is utilizing the 6-base genome to investigate the dynamics of enhancer DNA ...
The researchers performed DNA sequencing on individual cells of the horseshoe crab gills and discovered a crab enhancer that, when placed in the genome of zebrafish, had gill activity. This ...