Scientists first observed the biological phenomenon of restriction and modification in the 1950s, but they did not identify and isolate restriction enzymes until the late 1960s. 3 In 1970, Hamilton ...
Enzymology in complex reaction systems Although enzymology was initially focused on purifying and investigating individual enzymes, it was recognized at the time that biology constitutes ...
The study is published in Nature Chemical Biology. Cells adopt a simple ... for ubiquitinated proteins that could explain the link between the enzyme USP53 and the cholestasis condition.