The enzyme AMP-activated protein kinase (AMPK) has been shown to be central to regulating several metabolic systems such as glucose uptake, oxidation of fatty acids, and insulin sensitivity, but the ...

Physical activity is not only important for fitness but also for overall health. This is confirmed by a new study, which identified PanK4 as a key regulator of energy metabolism in skeletal muscle, ...

Furthermore, animals with a muscle-specific deficiency of PanK4 exhibited an increased fat content and impaired fatty acid oxidation within ... key players like mTOR, AMPK, and Akt.

Furthermore, the study demonstrates that treatment with Melye-amiley leads to the upregulation of thermogenic protein expression via the AMPK signaling ... and enhances fatty acid β-oxidation ...