A gene-edited mouse with two male parents has survived to adulthood, pushing new progress on stem cell research.

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

A research group led by Wei Li at the Chinese Academy of Sciences has created mice born from two male parents and capable of ...

To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene of interest. This may be done by deleting portions of the gene's DNA sequence to make it nonfunctional ...

Genetic changes are a significant cause of infertility, impacting over 15% of the global population. TLE6, a major protein involved in early embryonic development, is known to affect female fertility.

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their ...

New study reveals that TLE6 protein deficiency causes male infertility in mice. These findings suggest potential genetic ...

Scientists uncover how Ffar4 regulates sugar cravings through gut microbiota, revealing pantothenate as a key mediator to curb sugar intake.

Researchers explored the role of the TLE6 protein in male fertility using a novel mouse model. TLE6 deficiency caused significant reductions in sperm count and motility and led to abnormal sperm ...

Researchers say study represents a resource that could also help to dissect Y-gene functions in other tissues.