Most eukaryotes also make use of small noncoding RNAs to regulate gene expression. For example, the enzyme Dicer finds double-stranded regions of RNA and cuts out short pieces that can serve in a ...
Our research in this area includes uncovering fundamental mechanisms that regulate how genes are turned on and off in normal cells and how the misregulation of these mechanisms can lead to cancer, as ...
The role of RNA in information transfer and catalysis highlights its dual functionalities. Our laboratory has a long-standing interest in RNA folding, recognition, and catalysis. We are especially ...
A new study has comprehensively analyzed “cis-regulatory elements” (CREs), which are the DNA sequences that regulate gene transcription. This work sheds light on how these elements contribute ...