However, this model made predictions ... 1 Holliday proposed that this recombination intermediate arises from the nicking of one strand in each of two separate homologous DNA duplexes, followed ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

(Note that a third model of recombination, synthesis-dependent ... The search for DNA homology and formation of the junction between homologous regions is then carried out within the catalytic ...