Both Setd2-CD and Setd2-KO mice exhibited embryonic lethality ... the generation of point mutation CD knockin animal models and direct comparison with KO models is considered an objective standard ...

double heterozygous mice had significantly higher right ventricular systolic pressures than single heterozygous mice. Conclusion These findings demonstrate that knockin of a human disease causing BMPR ...

This research, conducted by a team at the Center for Synaptic Brain Dysfunctions within the Institute for Basic Science (IBS) led by Director KIM Eunjoon, reveals that lithium can restore brain ...