The Knockout Mouse Phenotyping Program (KOMP2) sites at Baylor College of Medicine, Jackson Laboratory, and University of California, Davis, are collaborating with the International Mouse Phenotyping ...

A knockout mouse is a laboratory mouse in which one or more genes have been turned off or "knocked out." To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene ...

They engineered mice with knockout mutations in two of these differentially methylated regions — one on chromosome 7, encompassing insulin-like growth factor 2 gene and H19, a gene for noncoding ...