They coined the term "receptor-mediated endocytosis" to describe the entry of LDL into the cells (Goldstein & Brown 2009). In another series of experiments, Brown and Goldstein used electron ...

Reduced receptor-mediated LDL endocytosis causing raised blood LDL cholesterol (LDL-C) is the main defect, but other abnormalities due to lack of LDL receptors include altered hepatic cholesterol ...

Heterologous expression experiments in Chinese hamster ovary cells reveal that scavenger receptor-BI (SR-BI) mediates the effects of HDL on the enzyme. HDL activation of eNOS is demonstrable in ...