Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

Techniques for delivering nucleic acids into mammalian cells have been around for decades. But tools and reagents continue to improve and target a broader range of cells and applications.

图 1. Attractene效率更高. DNA (pGFP which expresses green fluorescent protein) was transfected into the cell types indicated using Attractene Reagent. Transfection were also performed with A Reagent F or B ...

Lipid nanoparticles have been studied since ... low tissue penetration and minimal transfection efficiency (how effectively mRNA material is delivered and expressed in target cells).

Intravenous; LNP: Lipid nanoparticle ... demonstrated significantly higher transfection efficiency and lower toxicity to lung cells when compared with 25-kDa PEI [54] Use well-established natural ...