In 1985, the Nobel Prize in Physiology or Medicine was awarded to Michael Brown and Joseph Goldstein for identifying the receptor that clears LDL particles from the bloodstream. High blood levels ...

It appears that oxidized LDL or oxidized cholesterol metabolites ... target genes may regulate cholesterol metabolism and have an impact on efflux mechanisms. Our current microarray analyses ...

Scientists have discovered a potential new treatment for familial hypercholesterolemia, inspired by signs seen in the Mona ...

"Dyslipidemia" refers to an abnormality within the lipid profile, encompassing a variety of disorders relating to elevations in total cholesterol, LDL, or TG, or conversely, lower levels of HDL.

Firstly, LLAB focuses on the production and characterization of therapeutic HDL-mimetic nanodiscs. High-density lipoprotein (HDL) plays a crucial role in cholesterol metabolism and is known to possess ...

the remaining LDL is removed by way of scavenger pathways at the cellular level. As LDL is taken up by receptors, free cholesterol is released and accumulates within the cells. LDL receptor ...