In 2004, fifty years after Novikoff and de Duve observed lysosomes under the electron microscope, Noboru Mizushima and colleagues at the Tokyo Medical and Dental University tracked the formation ...
Using cryo-electron microscopy (cryo-EM), the researchers ... that this interaction is critical for lysosome transport. "Lysosomal dynamic transport is essential for the growth and invasion ...
Golgi thought that these intracellular membranes were interconnected, but advances in microscopy and biochemical ... The ER, Golgi apparatus, and lysosomes are all members of a network of ...