Tumor-associated macrophages (TAMs) are a critical component of the tumor microenvironment (TME) and play complex roles in cancer progression and treatment response. These immune cells can either ...
The research focused on macrophages, a type of immune cell critical for maintaining tissue health and fighting infections. In the tumor microenvironment, macrophages are usually reprogrammed to ...
Surrounding these epithelial cells is a microenvironment of supporting ... effects on lymphocytes and indirectly by tuning tumor-associated macrophages function.
An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...
Finding ways to tackle tumour associated macrophages, part of the “tumour microenvironment” that ... This will involve moving its first cancer drug into clinical trials, and starting work ...
The pro-inflammatory M1 macrophages and inflammation-related ... of new targeted therapies that precisely influence the tumor microenvironment and immune cell interactions, ultimately leading ...