Tumor-associated macrophages (TAMs) are a critical component of the tumor microenvironment (TME) and play complex roles in cancer progression and treatment response. These immune cells can either ...

Surrounding these epithelial cells is a microenvironment of supporting ... effects on lymphocytes and indirectly by tuning tumor-associated macrophages function.

The research focused on macrophages, a type of immune cell critical for maintaining tissue health and fighting infections. In the tumor microenvironment, macrophages are usually reprogrammed to ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

The tissue adjacent to a tumor behaves differently than areas farther away. The tumor's cancerous cells influence their ...

Explore how immune time-resolved Förster resonance energy transfer (iFRET) offers new insights into predicting immunotherapy ...

Finding ways to tackle tumour associated macrophages, part of the “tumour microenvironment” that ... This will involve moving its first cancer drug into clinical trials, and starting work ...

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell ...

We identified that in the liver, metastasis-associated macrophages with opposite ... Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis, Nature ...

“By doing this in a time course, in a dynamic manner, that really allowed us to identify the key networks within the tumor microenvironment ... and anti-inflammatory treatment with the original ...