Translating mouse models into clinical therapies has never been easy. Immunotherapies for cancer also have to contend with an approval process designed for testing drugs. It may be necessary to ...

Scientists say identification of two epigenetically different states in mouse model opens door to "entirely new world of ...

A revolutionary new treatment for breast cancer has shown the ability to eliminate small breast tumors and significantly ...

The typical treatment for estrogen receptor positive (ER+) breast cancer involves surgery and years of hormone therapy that ...

Researchers identify glucose usage as one major divergence betweenT cells expanding in vitro versus those expanding in vivo.

Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment ...

Learn how early developmental patterns can influence your lifetime cancer risk and the type of cancer that may develop.

Researchers have revolutionized cancer immunotherapy by developing a way to grow T cells in the lab that live longer and ...

Our laboratory is interested in the use of mouse models of prostate cancer to explore the pathogenesis of prostate cancer and its response to treatment. We have used the SV-40 based TRAMP model of ...

SIL-204 administered in an extended release formulation reduced tumor growth by ~50% after 30 days, with ~50% of tumors showing complete necrosis, in human pancreatic tumors harboring a G12D mutation ...