Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller ...

Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller ...

In addition, molecular interactions control the way that cells communicate with each other ... Within a decade, this unconventional microscope has evolved into a multifunctional toolbox.

What Is Atomic Force Microscopy? Atomic force microscopy (AFM ... molecular interactions, surface charges, and mechanical properties. During AFM imaging, scientists mount the sample on a piezoelectric ...

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

Researchers use atomic force ... in microscopy 1,2 have facilitated the detailed characterization and visualization of large macromolecular assemblies, AFM-generated surface topology maps can portray ...

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

For this, he uses a soft substrate and high-resolution live-cell fluorescence microscopy and develops novel force reconstruction technique, image modeling and machine learning technique to probe ...

In Kelvin probe force microscopy, a conducting cantilever is scanned over a surface at a constant height while an AC+DC potential is applied. The AC signal is a sinusoid whose frequency matches the ...

AFAM has applications in biophysics and biomedical research, particularly in the characterization of biological tissues, cells, and biomaterials. It can map the elastic properties of living cells, ...