The laboratory mouse is widely considered the model organism of choice for studying the diseases of ... producing either 'knock outs' to cripple gene function or 'knock ins' to introduce an ...

You are more like a mouse than you might think! Today, scientists are creating models of ... disease under study. Common directed techniques include transgenesis, single-gene knock-outs and ...

Knockout and knock-in in vivo models provide important insights into the normal behavior of a target gene. For example, ...