we exposed mouse and human intestinal organoids (self-organized 3D tissues derived from intestine-resident stem cells) to RANKL. We observed a reorganization and marked expansion of the intestinal ...

When is food simply nourishing and enjoyable, and when does it provoke an allergic reaction? The answer appears to lie in the ...

Our approach to organoid culture and differentiation involves the use of synthetic matrices to direct morphogenesis through tunable biochemical and mechanical signals. We spatiotemporally pattern ...

"We were able to grow and maintain organoids long term from human intestinal and airway cells, mouse intestinal cells, and even snake venom gland cells," Wijnakker explains. The cells maintained ...

The versatility of this Invasin coating is remarkable. “We were able to grow and maintain organoids long term from human intestinal and airway cells, mouse intestinal cells, and even snake venom gland ...

Researchers have pinpointed an intestinal protein that influences gut microbes, causing the body to become intolerant to ...

The creation of the first organoids in 2009 from intestinal stem cells opened up a world of new possibilities in biological ... his team at the National Cancer Institute have now established 3D ...

Intestinal organoids allow researchers to investigate organ development and patient-specific disease pathology; however, building this tissue accurately in vitro poses several challenges. Matthias ...

Want to say goodbye to food allergy? Targeting the gut protein RELMb could restore immune tolerance and potentially cure or prevent food allergies.