Studies show under-representation of children and teens with multidrug-resistant TB, calling for focused case-finding efforts ...

Antimicrobial resistance (AMR) has emerged as one of the leading public health threats globally, including South Africa ...

Evidence has emerged about the way bacteria become resistant to multiple drugs. The findings by a John Innes Centre research ...

DLBCL 作为最常见的淋巴瘤类型，虽然一线联合化疗免疫疗法对部分患者有效，但复发或难治性（rel/ref）患者的预后依旧很差。B 细胞受体（BCR）下游信号传导在 DLBCL 进展中起着关键作用，尤其是活化 B 细胞（ABC）起源的肿瘤，需要 CARD11 - BCL10 - MALT1（CBM）复合物激活 NF - κB。在 DLBCL 中，存在众多导致 CBM ...

肿瘤细胞的有氧糖酵解（Warburg 效应）与多种恶性行为相关，且乳酸衍生的组蛋白赖氨酸乳酸化是一种新型表观遗传修饰，可直接增加染色质内的基因转录。神经元前体细胞表达发育下调蛋白 4（NEDD4）作为 HECT 结构域 E3 连接酶家族的重要成员，在肿瘤细胞的多种过程中发挥关键作用，但 NEDD4 是否参与奥沙利铂和 5 - 氟尿嘧啶耐药的 HCC 发展尚不明确。

Multidrug-resistance is a significant challenge in eliminating the bacterial disease, as the complication increases treatment ...

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually. By 2050, the ...

The following is a summary of “Carbapenemase production and in-hospital mortality associated with multidrug-resistant ...

Study finds three new safe and effective drug regimens to fight multidrug-resistant TB. The treatments, which include recently discovered TB drugs, give new options for shorter, personalized treatment ...

A tuberculosis (TB) patient is said to be multidrug-resistant when the bacteria strain causing the infection has become ...