This includes rare mitochondrial genetic disorders as well as more common diseases such as diabetes, cancer, cardiovascular disease and neurodegenerative disorders—in which lower muscle function ...

Transformations in mitochondria function are seen before the loss of muscle mass and function, and experimental evidence in rodents, as well as humans, has resulted in the strong suggestion that a ...

Scientists identify a signaling pathway that triggers muscle fatigue in response to nervous system inflammation or infections ...

Muscle oxygen-binding proteins circumvent anatomical limits to enhance oxygen diffusion in multicellular organisms ...

They compared mitochondrial function in two groups of people over 60—healthy, active people and ‘prefrail’ people, whose muscle function had already declined. Using a benign radioactive ...

Muscle aging likely has several underlying factors, including decreased numbers of muscle stem cells, mitochondrial dysfunction, a decline in protein quality and turnover, and hormonal deregulation.