Freshly isolated NK cells, but not natural killer T cells or ... of a new member of the TNF family that induces apoptosis. Immunity 3, 673–682 (1995).

Scientists from the University of Pennsylvania have developed an innovative cancer treatment using small extracellular ...

New in vivo evidence confirms that tumor-expressed Fas ligand impairs immune responses to cancer by inducing apoptosis of anti ... of the intraperitoneal NK cell population 6.

Intracellular checkpoint molecules like BIM, which mediates apoptosis in NK cells, can be targeted to enhance antitumor responses. The absence of BIM in NK cells has been shown to increase their ...

Activation of this receptor triggers a self-destruction process of cancer cells, known as apoptosis. This approach has shown superior efficacy compared to antibodies targeting DR5, previously ...

Nano-sized, tumor-targeting particles induced self-destruction of cancer cells in preclinical studies. A new twist on a decades-old anticancer strategy has demonstrated significant potential against v ...

An approach using engineered small extracellular vesicles from NK cells to DR5 could be a promising strategy for solid tumors ...

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

Engineered extracellular vesicles show promise in targeting cancer cells and immunosuppressive stromal cells, offering a groundbreaking dual-action cancer therapy with minimal toxicity.

When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis ... the team used sEVs made by natural killer (NK) cells, a type of immune cell that frequently ...