RNA abundance is regulated by balancing transcription and degradation in processes that control the temporal and spatial distribution of cellular RNA. In eukaryotic cells, mRNA decay is catalyzed by ...

Overall, the research emphasizes the complexity of RNA degradation pathways and the critical roles played by the RNA exosome and its associated complexes. Understanding these mechanisms is ...

Deployment of small RNA pathways for spatiotemporal regulation ... slicer-dependent and slicer-independent degradation of transcripts, and transcript localization were reviewed recently in Ref.

Most people associate sunburns with DNA damage -- it's what we've been taught in textbooks and by dermatologists for years.

In our body, this role is played by so-called RNA modifications ... "Its function: When m6A is attached to an mRNA, it triggers the degradation of the mRNA as soon as the first proteins have ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Dr. CHAO Yanjie at the Shanghai Institute of Immunity and Infection of the Chinese Academy of Sciences and Dr. WANG Chuan from Fudan University revealed how a bacterial pathogen coordinates ...