Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

The team suspects that animals with almost translucent bodies may have yet more systems to detect light directly.

A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling ...

Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

They also realized that the β-adrenergic receptor was one of many in a whole family of receptors that function in the same way. This family is now known as G-protein-coupled receptors, and the studies ...

The spike protein of the coronavirus, or SARS-CoV-2, binds to ACE2, a receptor on the host cells, which allows the virus to enter the cells and infect it. Binding is the first step for infection, and ...

The Sudan virus, a close relative of Ebola, has a fatality rate of 50% but remains poorly understood in terms of how it infects cells. Currently, no approved treatments exist. To address this critical ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their ...

Their study, published recently in Nature, focuses on what is known as the estrogen receptor, a protein linked in previous research to the development of roughly 70% of all breast tumors.