Several mutations affecting β-amyloid, either to APP 1,2,3 ... compared to littermate controls so that age and background strain were comparable. There were, however, small generational ...
Ever since Alois Alzheimer first described the neurological changes that characterize the disease that now bears his name, amyloid plaques have been a central focus of AD research. By the early ...
The team also discovered that the amyloid proteins come in different strains, like viruses, and drugs which target the main strain could allow less dominant forms to develop, which are untreatable.