Nature Chemical Biology - Excitatory synapses are located in confined chemical spaces called the dendritic spines. These are atypical femtoliter-order microdomains where the behavior of even single ...

When naive T cells encounter antigen-presenting cells (APCs), membrane and cytoplasmic molecules rearrange at the T cell–APC contact area to form the immune synapse. Finetti et al. now reveal an ...

A new collaboration has unlocked new potential for the field by creating a novel high-performance organic electrochemical neuron that responds within the frequency range of human neurons.

A study in the journal Pharmaceuticals has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...

A multi-disciplinary team has found that depriving lab mice of sleep can lead to a reduction in synapse diversity in the brain. In their study, published on the open-access site Current Biology ...

In a previous study, the Project Group Translational Deep Phenotyping at the Max Planck Institute (MPI) of Psychiatry, headed by Florian Raabe, found alterations in the retina of schizophrenia ...