In 5’ to 3’ order, it usually includes the mitochondrial membrane translocase gene TOMM40, APOE, and the apolipoprotein genes of the APOC1-C4-C2 gene cluster. Some studies also include genes upstream ...
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Study reveals that almost all individuals with two copies of the APOE4 gene develop signs of Alzheimer'sThe study, published in Nature Medicine, also concludes that those individuals homozygous for APOE4 also develop the disease earlier than those with other variants of the APOE gene. These findings ...
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