Autophagy, the cell's essential housekeeping process, involves degrading and recycling damaged organelles, proteins, and other components to prevent clutter. This vital mechanism, found in all life ...

More than a decade of research shows that the nucleolus—the largest structure in the eukaryotic nucleus—plays a pivotal role in aging. Now, a new study analyzing yeast cells suggests both that the ...

However, the yeast two-hybrid system is limited to studying proteins that can translocate to the nucleus and do not display any autonomous capacity for activating transcription 2. Thus ...

To test this idea, they engineered an artificial way to secure rDNA to the membrane surrounding the nucleus of yeast cells so they could control when it was anchored and when it was not.

To the growing list of factors required for the export of messenger RNA from nucleus to cytoplasm can now be added Yra1. Yeast Yra1 and its metazoan orthologues bind mRNAs and interact with ...

Against this backdrop, a research team from Japan recently focused on an autophagy pathway that degrades a part of the nucleus (macronucleophagy) in Saccharomyces cerevisiae, a species of yeast ...