Fission yeast and budding yeast are free-living haploid cells that are easily grown in the laboratory. They have different cell shapes and patterns of division. Left, fission yeast; right ...

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

One of their favorite test subjects is the yeast species S. pombe, used for centuries in traditional brewing. As a eukaryote, ...

The Noguchi Lab works with mammalian cells and fission yeast (Schizosaccharomyces pombe). Fission yeast is an exceptional model system for studying cell cycle control and genome maintenance mechanisms ...

pombe (Fowler et al. 2014) and mouse ... Interactions between chromosomes, dependent on ZMM proteins in yeast, feed back to inhibit Spo11. C. DSB formation is temporspatially coordinated with DNA ...

The study not only indicates the presence of RNAi in some budding yeast species ... function in these organisms from its role in S. pombe. In addition, the mechanism by which an enzyme lacking ...

My laboratory conducts molecular genetic and chemical genetic research using the fission yeast Schizosaccharomyces pombe. Initially, we studied how extracellular glucose triggers repression of ...

Structure of the yeast 12-subunit nuclear exosome We pioneered methods to ... Mtr4-containing RNA exosomes from Saccharomyces cerevisiae, Schizosaccharomyces pombe, and human and show that they can ...