Mitochondria, the powerhouse of the cell, plays a crucial role in reshaping the metabolic reprogramming of cancer cells and TILs.

Currently, it is difficult to predict the way in which mtDNA mutations will pass from mother to child due to the interplay between the mitochondrial and nuclear genomes. It is clear, however ...

Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune system. It essentially hacks the immune cells, transferring its own faulty ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

The other approach analyzes mitochondrial DNA, or mtDNA. Because mtDNA tends to survive long after nuclear DNA has disintegrated, this approach is useful in identifying the remains of persons who ...

But using sequencing data from the mitochondrial genomes of members from three unrelated families, researchers have identified 17 individuals who inherited mtDNA from both parents. The results were ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

Roman writers found the relative empowerment of Celtic women in British society remarkable. People today shouldn’t.

Explore how psychosocial and physical stress affects cfDNA release in blood and saliva. Discover gender differences and ...

通过线粒体转移，癌细胞不仅实现了对T细胞功能的精确抑制，还为其免疫逃逸增加了一道屏障。该研究进一步指出，这种机制与免疫治疗效果不佳密切相关，尤其是在携带大量mtDNA突变的患者中，免疫检查点抑制剂的疗效显著降低。