the authors addressed this issue by adding polyaspartate tags to the termini of the Cas protein, enabling effective genome manipulation in Streptomyces. A comprehensive analysis of Cas9-induced ...

The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it ...

For each of two nucleases—Cas9 from Streptococcus pyogenes ... biochemist David Baker that develops structure-based computational tools to design proteins that evade the immune response.