1 Department of Clinical Neurology, The Royal Hallamshire Hospital, Sheffield, UK 2 Department of Gastroenterology, The Royal Hallamshire Hospital Correspondence to: Dr M Hadjivassiliou, Department of ...

OBJECTIVES Neuropsychological investigations have shown a degree of cognitive dysfunction in a proportion of non-demented patients with ALS. Respiratory muscle weakness in ALS can lead to nocturnal ...

1 Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA 2 Johns Hopkins University School of Medicine 3 Department of Neurosurgery, Johns Hopkins ...

University of Iowa, The Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA Objective: The objective of the Predict-HD study is to use genetic, neurobiological and refined clinical ...

2 Departments of Neurology, Hôpital de la Salpêtrière, Paris Cedex 13, France 3 Departments of Neurosurgery, Hôpital de la Salpêtrière 4 Departments of Neuroanaesthesiology, Hôpital de la Salpêtrière ...

Background Cognitive dysfunction is a major feature of Parkinson’s disease (PD), but the pathophysiology remains unknown. One potential mechanism is abnormal low-frequency cortical rhythms which ...

Department of Clinical Neurosciences, University of Cambridge Clinical School, Addenbrooke’s Hospital, Cambridge CB2 0QQ, UK N Robertson, Helen Durham Neuro-inflammatory Centre, Department of ...

Adult-onset leukodystrophies and genetic leukoencephalopathies comprise a diverse group of neurodegenerative disorders of white matter with a wide age of onset and phenotypic spectrum. Patients with ...

Objective To evaluate the efficacy and safety of intramuscular ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis (ALS). Methods 373 patients with ALS (El Escorial definite ...

As a chronic progressive disease, Parkinson's disease (PD) has a presymptomatic interval; that is, a period during which the pathological process has begun, but motor signs required for the clinical ...

1 Department of Microbiology, Royal Brompton and Harefield NHS Trust, Imperial College School of Medicine, London, UK 2 Department of Tissue Typing, Royal Brompton and Harefield NHS Trust 3 Department ...

Correspondence to Dr Masahiro Mori, Neurology, Chiba University Graduate School of Medicine School of Medicine, Chiba, Chiba, Japan; morim{at}faculty.chiba-u.jp Objective To investigate longitudinal ...