Our data set consists of 449 SNPs distributed in the 57 CYP450 genes. FastSNP analysis predicted the functional impact of these genetic variants: 47.9% of the SNPs have no known function ...

Institute of Molecular Metrology, College of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, P.R. China ...

Department of Earth, Planetary, and Space Sciences, University of California, Los Angeles, California 90095, United States ...

Mesoblast (ASX:MSB) was the top performer for the year up 835% (as of December 30). On December 18 Mesoblast announced that the US Food and Drug Administration (FDA) had finally approved its therapy ...

FIGURE 2. P450-active cycle exemplified for GPA crosslinking together with the heme oxygenase degradation pathway. PCP-X construct. The PCP-X construct from the kistamicin NRPS was expressed and ...

In vitro human studies show that the metabolism of most amphetamine-like psychostimulants is regulated by the polymorphic cytochrome P450 isozyme CYP2D6. Two compounds, methamphetamine and ...

Most recent attention has been paid to the role of superoxide. There are many enzymatic sources of superoxide including NADPH oxidase, xanthine oxidase, nitric oxide synthase, and cytochrome P450. The ...