Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...
This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...
Cyclin destruction can order late mitotic events. What function is served by destroying ... reveal a broad range of activities (L. Holt and D.O.M., unpublished observations), and some Cdk targets ...
Having a D+, D, or D- may mean that you miss out on a spot as a government-sponsored student in a higher learning institution in Kenya. However, this is not the end of the road because there are many ...
This scientist says, “A Department of Defence R&D functions like any other department of the Government of India, like the Ministry of Agriculture, broadly, in terms of the rules.” Government ...
Injecting infarcted pig hearts with specially bioengineered cells significantly decreased the infarct area and improved heart function, showing possible clinical ... led by Jianyi “Jay” Zhang, M.D., ...
Every nutrient has unique functions. Deficiencies in a specific vitamin or mineral ... Low-fat and fat-free dairy milk, kefir, yogurt, and cottage cheese contain calcium, vitamin D, potassium, and ...