ATR and ATM kinases are key factors for the surveillance of DNA replication, and prevent chromosome breakage in dividing cells. However, during repair processes, chromosome fragments can be ...

Aa Aa Aa Eukaryotic genomes are replicated with almost absolute fidelity every time cells divide. However, conditions for DNA replication are rarely ideal. For example, environmental toxins or ...

DNA replication is happening continuously throughout the body, as many as trillions of times per day. Whenever a cell divides ...

DNA replication is happening continuously throughout the body, as many as trillions of times per day. Whenever a cell ...

DNA replication is happening continuously throughout ... For example, in cancer -- marked by rapidly dividing cells -- a medicine could potentially kill the cells by accessing them during the ...

Combining long-read DNA sequencing with a predictive artificial intelligence model has provided new insights into DNA ...

In a study that appears in the journal Cell, scientists from San Francisco-based Gladstone Institutes—including co-first author Megan Ostrowski (left) and senior author Vijay Ramani, ...

Most dividing cells in the body have well-defined checkpoint mechanisms to sense and correct DNA damage during DNA replication. Neurons, however, do not divide. For this reason, they are at ...

These drugs interfere with DNA synthesis and replication, leading to the death of rapidly dividing cancer cells. Pyrimidine derivatives, such as leflunomide and teriflunomide, are used as ...