Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

DNA (deoxyribonucleic acid), the molecular "blueprint" carrying the genetic instructions that influence the growth, ...

RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...

New study by Chiba University, Japan in collaboration with Karolinska Institutet, Sweden, uncovers novel enhancer-promoter interactions that regulate gene expression during neuronal differentiation ...

[101] This sequence, which is known to induce DNA curvature, may serve to bring together proteins that bind at sites flanking this motif. Examination of the other insulin promoters reveals that ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...