As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The following is a summary of “Identification of a pancreatic stellate cell gene signature and lncRNA interactions associated with type 2 diabetes progression,” published in the January 2025 issue of ...

14 Southern California Research Center for ALPD and Cirrhosis, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA The field of pancreatic stellate cell (PSC ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

This study uses a variety of approaches to explore the role of cerebellum, and in particular Purkinje cells (PCs), in the development of postural control in larval ... Statistical methods that account ...

These simulations can be used to help understand the computational contributions of various cerebellar components, including the relevance of the enormous number of neurons in the granule cell layer.

This important study successfully applies an innovative chemogenetic tool to investigate cerebellar function to advance our understanding of the contributions of Purkinje cell populations to postural ...

Jan. 28, 2025 — The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been ... Keeping the Steps of Cell ...

This study aims to identify gene expression patterns specific to T2D pancreatic islet cells and to explore the potential role of pancreatic stellate cells (PSCs) in T2D progression through regulatory ...

Background and aims: Thrombospondin 1 (TSP-1) is an important activator of latent transforming growth factor β (TGF-β) but little is known of the expression patterns and functions of TSP-1 in liver ...

Institute of Biology, University of Szczecin, Szczecin, Poland Department of Human Immunology, Institute of Medical Sciences, University of Rzeszow, Rzeszow, Poland Swiss Institute of Allergy and ...

Together, our findings indicate that the motor dysfunction in ASD are affected by Trio deletion in PCs with delayed in onset, accompanied with alterations in MRI, histological, and epigenetic level.